The Scottish singer - whose debut album 'I Dreamed a Dream' was the fastest-selling debut LP ever released by a woman - will team up with the Italian operatic legend for a new TV talent show even though she beat him in the US album charts.
The pair will join together for upcoming ITV1 show 'Pop Star to Opera Star', where pop musicians will compete against each other by singing classical arias.
A source told The Sun newspaper: "Susan has held Andrea off the top of the US charts for weeks - it's incredible. But he holds no grudges, he joked that he 'must sing with this amazing woman.' "
The blind tenor's latest album, 'My Christmas', was kept from the Billboard top spot by 48-year-old spinster Susan's LP.
When they perform together, the pair are expected to duet on one of Grammy-nominated Andrea's most famous songs - either 'Time To Say Goodbye', which he famously performed with Sarah Brightman, or 'The Prayer', which he sang with Celine Dion.
Susan shot to fame earlier this year when she appeared on British TV show 'Britain's Got Talent' - on which she finished second.
Since releasing her award-winning album earlier this year, Susan has already fulfilled her lifelong dream of performing alongside musical legend Elaine Paige.