The funnywoman was among the thousands who tuned in to watch the actress' self-titled reality series on Oprah Winfrey's Own network, and expressed her shock at the seemingly chaotic state of Lohan's life.
O'Donnell tweeted, "The Lindsay show is a tragedy - on every level. I hope one day she gets sober for real and watches these episodes - n (and) sees what we all do."
The tweet irked Lohan, who hit back by saying the comments were "really sad", and now O'Donnell has taken to her blog to explain what she said.
In poetic style, the actress/broadcaster writes, "I watched only one episode, Ll (Lindsay Lohan) looking lost - late for work again and again scared suffering - surrounded by sycophants.
"We r (are) asked to watch but not see what is right in front of r (our) eyes to nod in complicity as everyone braces for impact.
"I tweeted the show was a tragedy 'an event causing great suffering, destruction, and distress' that's what it felt like to me start to finish (sic).
"I wish only for Lindsay's healing for sobriety that will serve her so for a calming of all demons that plague her for stillness inside her soul.
"I have compassion for the little girl I see beneath the designer duds (clothes), one that could use a safe place to land maybe for the first time in her life."
The series came to an explosive end on Sunday (20Apr14) when the Mean Girls actress revealed she had suffered a miscarriage during filming.
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