The boyband leads the nominations along with Perry and Gomez, who have all scored three nods each, and they will all compete in the Song of the Year category for Best Song Ever, Roar and Come & Get It respectively.
One Direction are also nominated for the Best Music Group trophy, alongside R5 and Emblem3, while their supporters, known as 'Directioners' are nominated in the Fiercest Fans category.
Perry also landed a nod in the fan category along with Taylor Swift, who will compete against the I Kissed a Girl hitmaker and Demi Lovato for the Best Female Artist prize.
Meanwhile Gomez will battle it out with British stars Olly Murs and Little Mix for the Best Song To Dance To award and the former Disney star is also in the running for Radio Disney's Most Talked About Artist alongside Austin Mahone and Ariana Grande.
The annual awards ceremony, which celebrates the most popular music stars among teenagers, will be held at Los Angeles' Nokia Theatre on 26 April (14). The prizes are decided by a public vote.