DeWanda Wise has dropped out of 'Captain Marvel'.

The 33-year-old actress was due to star alongside Brie Larson in the Marvel Cinematic Universe (MCU) movie - which will be the first Marvel movie to star a female superhero as the lead role - but Deadline has now reported she's been forced to drop out of the production.

Sources have claimed to the publication that DeWanda's decision to leave 'Captain Marvel' came after ''scheduling conflicts'' with her hit Netflix series 'She's Gotta Have It', where she stars as Nola Darling.

The Netflix series - which is based on Spike Lee's 1986 movie - was renewed for a second season in January, just after DeWanda joined the cast of the upcoming Marvel flick.

'Captain Marvel' was set to be the first major movie role for DeWanda, whose replacement has not yet been cast.

Meanwhile, other stars joining Brie - who will star as Carol Danvers and her crime fighting alter-ego - on the big screen include Jude Law, Ben Mendelsohn, and Samuel L. Jackson, who will be reprising his role as fan-favourite Nick Fury.

Ben Mendelsohn is known to be starring as the villain, and although his exact role is not yet know, Marvel Studios boss Kevin Feige previously teased that the shape-shifting alien group known as the Skrulls would feature in 'Captain Marvel'.

The story follows Air Force pilot Carol whose DNA is fused with that of an alien in an accident, giving her super strength, energy projection and flight powers.

While the details of the motion picture are being kept tightly under wraps, Feige announced at the San Diego Comic Con this year that the film will be set in the 90s, meaning this will take place before the events of the 'Avengers' movie.

Anna Boden and Ryan Fleck are directing the production, which has been slated for a March 8 2019 release.