Rapper Nelly has scored his fourth US number one single after topping the new chart with his latest release GRILLZ.

The ode to jewelled teeth, which features Paul Wall and ALI + GIPP, jumped up from number five to topple LAFFY TAFFY by D4L for the top spot.

It's Nelly's first number one since SHAKE YA TAILFEATHER in 2003.

Chris Brown's former chart-topper, RUN IT!, holds firm at number two, while Beyonce Knowles' new hit CHECK ON IT rockets up the chart to number three.

Reggae star Sean Paul's TEMPERATURE is the Hot 100's highest new entry, debuting at number 74.