The SPECIAL TWO hitmaker, 22, picked up Best Pop Album, Highest Selling Album, Breakthrough Album and Album of the Year for THE SOUND OF WHITE, as well as Best Female Artist at the star-studded ceremony in Sydney's Superdome.
Rocker Ben Lee was the second big winner of the night, triumphing in the Single Of The Year, Best Independent Release and Best Male Artist.
Western Australian band Eskimo Joe were named Best Group, and made their night even more special when guitarist STU MacLEOD proposed to his girlfriend live during the televised show.
The full list of winners are:
Album of the Year - MISSY HIGGINS, THE SOUND OF WHITE
Single of the year - BEN LEE, CATCH MY DISEASE
Breakthrough Artist - Album - MISSY HIGGINS, THE SOUND OF WHITE
Breakthrough Artist - Single - END OF FASHION, O YEAH!
Best Group - ESKIMO JOE
Best Male Artist - BEN LEE
Best Female Artist - MISSY HIGGINS
Best Rock Album - GRINSPOON, THRILLS KILLS AND SUNDAY PILLS
Best Country Album - KEITH URBAN, BE HERE
Best Blues and Roots Album - MIA DYSON, PARKING LOTS
Best Children's Album - THE WIGGLES, LIVE HOT POTATOES
Best Dance Release - Infusion, SIX FEET ABOVE YESTERDAY
Best Urban Release - Daniel Merriweather, SHE'S GOT ME
Best Adult Contemporary Album - THE GO-BETWEENS, OCEANS APART
Best Pop Release - MISSY HIGGINS, THE SOUND OF WHITE
Best Independent Release - BEN LEE, AWAKE IS THE NEW SLEEP
Best Comedy Release - TRIPOD, MIDDLEBOROUGH ROAD
Best Music DVD - JET, RIGHT RIGHT RIGHT
Highest Selling Album - MISSY HIGGINS, THE SOUND OF WHITE
Highest Selling Single - ANTHONY CALLEA, THE PRAYER
ARIA Awards Hall of Fame Inductee - JIMMY BARNES.