The star will become the first female recipient of the prize when she is presented with the accolade at the California ceremony, following in the footsteps of previous honourees Kevin Hart and Will Ferrell.

MTV bosses chose Melissa as the winner of the Comedic Genius Award in recognition of her "bold and fearless comedic style" in films like Bridesmaids, Spy, The Heat, Tammy, and Identity Thief, and her TV series Mike and Molly, while they have also taken note of her work behind the scenes.

"Honoring Melissa McCarthy with MTV's Comedic Genius Award is exciting on so many levels," MTV executives announce in a statement. "It's the first time this award is going to a woman, which is fantastic.

"We love Melissa for her performances but she also writes, produces and directs comedy, so this award is incredibly well deserved. The most exciting thing about Melissa is how brave she is; you don't want to miss her moment in the show."

Melissa already has two MTV Movie Awards to her name, after previously winning the Best Comedic Performance and Best Gut-Wrenching Performance for her breakout role in 2011's Bridesmaids.

She will also have the chance to add another pair of accolades, for Best Comedic Performance and Best Fight, to her trophy cabinet after scoring the nominations for her turn in Spy.

Melissa isn't the only big name to land a special honour. Will Smith will pick up the MTV Generation Award in celebration of his Hollywood legacy.

The 25th annual MTV Movie Awards will be hosted by Dwayne Johnson and Kevin Hart.