The former Desperate Housewives actress helped organise the star-studded event at the ME Hotel in London on behalf of a number of good causes including the Eva Longoria Foundation, which helps fellow Latinas better themselves through education and entrepreneurship.
Spice Girls singer Brown hosted the event, while the audience was entertained by performances from British magician Dynamo and girl band Stooshe.
Brown raised $24,000 (£15,000) by auctioning off two tickets to see the new Spice Girls musical Viva Forever! along with a meet-and-greet session, but the successful bidder turned out to be her husband, Stephen Belafonte.
Rapper will.i.am was presented with the Special Humanitarian Award, while John Caudwell, who founded the Caudwell Children charity to help sick and disabled kids, was honoured with the Lifetime Achievement Award.
Longoria took to her Twitter.com to share snaps from the bash and wrote,"Great night!... It was a successful, beautiful event."