Lou Reed succumbed to liver disease at his home in Long Island, New York, according to the late rocker's doctor.
The former Velvet Underground frontman died on Sunday (27Oct13) after battling poor health for months.
Dr. Charles Miller, who performed a liver transplant on Reed at the Cleveland Clinic in April (13), tells the New York Times that the rocker returned to Ohio last week (bes21Oct13) for further treatment.
The medic told Reed his condition could no longer be treated, and the singer/songwriter opted to return to the home he shared with his wife Laurie Anderson.
The doctor says, "We all agreed that we did everything we could."
Tributes from the music world have been pouring in for Reed since news of his death was released. Blondie stars Debbie Harry and Chris Stein and Talking Heads frontman David Byrne added their thoughts about the rock star in statements on Monday (28Oct13).
Harry wrote, "I'm so sad that he's gone but his hypnotic voice telling a story of a Perfect Day, or the devil let loose in White Light/White Heat will live forever."
Her bandmate Stein added, "Lou was one of a handful of originals. I don't think that the conditions that created him will again even be approximated, let alone duplicated."
And Byrne stated, "His work and that of the Velvets was a big reason I moved to Ny and I don't think I'm alone there. We wanted to be in a city that nurtured and fed that kind of talent."