The 61-year-old showbiz matriarch and the Olympic gold medal-winning star shared a 23-year marriage together - but Kris filed for divorce in September 2014, shortly before Caitlyn came out as a transgender woman.
Kris shared: ''I've really tried to be a good friend. I try to be very understanding of how it must feel like to navigate a big huge family.''
Kris and Caitlyn, who was known as Bruce Jenner prior to undergoing gender reassignment surgery, have two biological children together, models Kendall and Kylie Jenner.
And Kris has insisted that despite the high-profile collapse of their marriage, she has maintained a good relationship with Caitlyn.
She told Us Weekly: ''Relationships change all the time ... I just try to be a good friend.''
Since her split from Caitlyn, Kris has been dating Corey Gamble, but the two-time divorcee has admitted she cannot envision herself tying the knot again.
She explained: ''I live my life by, 'Tomorrow's not promised and today is really amazing.' I'm really happy with how things are right now.''
However, Kris has offered some advice to people who are embarking on marriage, insisting that communication and a healthy sex life are two key ingredients.
She said: ''It's old fashioned, but never go to bed angry and always communicate - and a little fabulous lingerie doesn't hurt!''
Meanwhile, Kanye West has reportedly been spending ''hours'' on the phone talking to Caitlyn about his recent problems.
The outspoken rap star - who was hospitalised in November amid reports he had suffered a breakdown - has turned to the 'I Am Cait' star for ''counselling'' as he gets back on track.
A source recently said: ''Caitlyn has been counselling Kanye over the past few months and they often talk for hours on the phone or at her Malibu home, which has become a refuge for him.
''He feels a deep connection with Caitlyn, who has had bouts of depression and struggled in the limelight, which Kanye can relate to.''
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