In a touching tribute to Alexandra McQueen - who committed suicide last week - both Naomi and Kate wore designs from his last Spring/Summer 2010 collection.
The event was organised by Naomi to raise money for survivors of the Haitian earthquake.
She said: "I am deeply saddened by the recent tragedy in Haiti.
"So many have been killed and severely affected by the earthquake - women and children in particular are most vulnerable in disasters. Fashion is universal, personal and touches everyone."
Comedians James Corden and David Walliams decided to make a statement at the event, passionately kissing each other when they got to the end of the runway.
One model, Tolula Adeyemi, had trouble with her platform heels and almost dived off the runway.
Writing on twitter, she said: "OMG almost took a tumble in thos shoes on Naomi's catwalk! 2 sizes 2 big! my falling from grace, almost, on Naomi Campbell's catwalk!!(sic)"