The 'Fire' hitmakers will close the event at Worthy Farm on Sunday, June 29, joining headliners Arcade Fire on Friday, June 27, while the Saturday headliner is yet to be announced.
Kasabian - made up of Serge Pizzorno, Chris Edwards, Tim Carter and Ian Matthews - will make their debut at the festival ahead of the release of their new album and Serge insists he can now ''die a happy man''.
He told NME.com: ''We knew we were in the running which was amazing. Being in the running is fine but you don't want to be in the race, you want to win it. You want to be on the podium. We got the phone call - I felt relieved because we've always wanted to do it from the first rehearsal, day one of the first rehearsal. We kicked into a tune and sort of went, 'Glastonbury!', a full on shout out.''
Michael's daughter Emily Eavis said: ''We always take great pride in putting a great British band on to headline the Pyramid [stage] and this time it's Kasabian, who are one of the most requested bands from Glastonbury-goers and an amazing live act. It's going to be one hell of a show!''
'Where Is My Mind?' hitmakers Pixies have not performed at the festival since 1989 and are set to release their fifth album, 'Indie Cindy', their first record in 23 years.
The festival has already sold out but a re-sale of tickets that have been cancelled or refunded will go back on sale to the public at the end of April visit Glastonbury.seetickets.com for more.