The co-creator and original star of the production is currently in the middle of his run as the titular transgender rocker, but during a performance at the weekend he sustained a knee injury.
He was able to finish the rest of the early show, but the 10pm performance that same night was cancelled.
According to a post from the official Hedwig Broadway Twitter.com account, Mitchell is in "good spirits" and has been consulting a doctor.
They are hoping Mitchell will return for the next scheduled performance on Tuesday (10Feb15).
Mitchell, who wrote the show with composer Stephen Trask and also directed and starred in the 2001 movie version, follows in the footsteps of Dexter star Michael C. Hall, Girls actor Andrew Rannells, and Neil Patrick Harris, who won a Tony Award for his performance as Hedwig last year (14).
Mitchell's run as Hedwig is slated to run until 26 April (15).
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