The 57-year-old made his name in Britain alongside comedy partner Stephen Fry in the 1980s before becoming a major star on U.S. television as acerbic clinician Dr. Gregory House.

Hugh, who was joined by Stephen for the ceremony on Los Angeles' Hollywood Boulevard, spoke about how lucky he felt to receive the coveted accolade, previously awarded to high-profile stars such as Marlon Brando, Frank Sinatra and Marilyn Monroe.

"This is not a fair world. I'm 57 now and I've lived a life of extraordinary good fortune from start to finish, so much so I'm anticipating a piano falling on my head to redress the balance," he said at the unveiling.

"I've been incredibly lucky. I'm going to bask in this extraordinary honour and my extraordinary good luck and I'll set to work first thing tomorrow on the global unfairness problem."

Stephen, who first met Hugh at university, acted as a guest speaker at the ceremony and praised his friend's kindness in his speech.

"While he may not be the first wise and kind star to be set in a paving slab in old Hollywood, I venture to suggest no star was ever wiser or kinder," he said.

The duo are well known in the U.K. for their sketch shows, appearances in historical comedy Blackadder and performances as author P.G. Wodehouse's literary characters Jeeves and Wooster.

However it is as Dr. House, whom Hugh played between 2004 and 2012, that garnered the actor a fan following in the U.S.

He won two Golden Globe Awards for the role, with the part establishing him as one of America's highest paid television actors.