Randall Whittinghill, a puppeteer and acting coach, has filed legal documents to end their marriage, citing irreconcilable differences.
The couple is heading to mediation to settle the division of property, while Whittinghill has also requested spousal support from Coupe, reports Tmz.com.
The blonde beauty married Whittinghill in 2007 after seven years of dating. They have no kids together.
The split comes just two months after Coupe's U.S. Tv sitcom Happy Endings was axed by network bosses after a three-season run.