The 'Not Afraid' rapper has used a section of the singer's vocals on a track he is expected to release as his big comeback this summer.
A source told The Sun newspaper: ''The song features the hook of one of Jamie's tracks and Eminem rapping the verses.
''It's scheduled to be Eminem's big single this summer when he headlines the Reading and Leeds festivals in the UK.
''Jamie already has a good buzz around him in the music industry but now Eminem's endorsement of him is a huge deal.''
Eminem famously helped kick start the career of another British singer, Dido, by sampling her track 'Thank You' for his 2001 hit 'Stan'. She subsequently went on to sell over 16 million copies of her debut 'No Angel'.
Jamie is signed to the record label run by producer Alex Da Kid, who is working on Eminem's new album, and previously produced his mega hit 'Love the Way You Lie' which featured Rihanna.
Another track on Eminem's album - the follow to 2010's 'Recovery' - features Lady Gaga and rapper Kendrick Lamar.
He said: ''Yeah, I got this crazy record with Gaga and Kendrick for the upcoming LP. Its called 'Street Lights', and its just a real upbeat record.''
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