Jeffry Aronsson is believed to have left Emanuel Ungaro.
The Fashion house's chief executive officer (CEO) - who joined the company in June to "heal the bruises" of the label - has reportedly stopped commuting to Paris and is believed to have permanently returned to his investment and consulting firm Aronsson Group.
However, Ungaro told WWD: "Mr. Aronsson is still the acting CEO of Ungaro."
If the executive's departure is true, it is the latest in a string of high-profile exits from the fashion house.
Giles Deacon became the sixth designer to leave in as many years when he quit in September after just two seasons.
Before his exit, the company has seen Giambattista Valli, Vincent Darre, Peter Dundas, Esteban Cortazar and Estrella Archs work short stints for them since their founder retired in 2004.
Following his departure earlier this year, Giles said he was "proud" of what he had achieved at the French fashion house but was keen to work ore with his Giles brand.
He said: "I am very proud of the work that I - and my team - did at Ungaro, and it was a pleasure to work in Monsieur Ungaro's studio and with members of his actual atelier
"I am going to concentrate on the global development of the Giles brand with some exciting one-off projects in the pipeline for next year - and I'm really excited about presenting the Giles spring/summer 2012 collection on Monday evening."