Eddie Redmayne is due to star in sex-change drama 'The Danish Girl'.

The actor will join forces with his 'Les Miserables' director Tom Hooper for the first time since they worked on the 2012 musical blockbuster.

The movie's screenplay, adapted by Lucinda Coxon, is based on David Ebershoff's 2001 book of the same name about the real-life love story of Danish painters Einar Wegener and his wife Gerda.

Wegener became one of the first men to have a sex change, officially becoming Lili Elbe in 1930, and the lead role will no doubt be a challenging one for Redmayne.

Hooper told The Hollywood Reporter: '' 'The Danish Girl' is an extraordinary love story and a story about finding your true self. I first read Lucinda's script when I was making 'The King's Speech' and I was so moved by this true story. I have wanted to make the film ever since.''

Hooper will be joined in his production duties by Pretty Pictures' Gail Mutrux, Anne Harrison and Linda Reisman, as well as Working Title's Erik Fellner and Tim Bevan.

The director, who previously won a Best Picture Oscar for 'The King's Speech', has yet to announce a follow up to 'Les Miserables', so this is likely to be his next project.

The film has had several failed attempts at adaptation, with Nicole Kidman,Charlize Theron, Gwyneth Paltrow and Rachel Weisz all previously considered for a lead role.