The 32-year-old actress was recently announced as the first openly gay superhero in a TV series, which she described as a ''game changer'', but Ruby has subsequently decided to delete her account on the micro-blogging site in response to the onslaught of negativity she's received.
And now the 'Shape of You' hitmaker - who quit Twitter himself last July after receiving negative comments about his cameo in the first episode of season seven of 'Game Of Thrones' - has reached out to defend 'The Meg' actress.
The 27-year-old singer/songwriter - who co-hosted the 2015 MTV European Music Awards with the 'Orange is the new Black' star - captioned a screenshot of an article announcing her casting on his Instagram Story: ''Yo @rubyrose - congrats on such an awesome role.
''Bugger what anyone else thinks, you're killing it x (sic)''
Ruby's final tweet before shutting down her account saw the model-turned-actress bemoan the reaction to her casting in the upcoming TV series.
By contrast, Ruby previously hailed the significance of the move, admitting she'd been overcome with emotion every time she'd stopped to think about her latest casting.
She said: ''I kept spontaneously crying and I kind of feel like I'm going to do it now, so I'm just going to...''
Ruby - who came out as a lesbian at the age of 12 - then explained that her casting as Batwoman has reminded her of her own childhood experiences.
She said: ''I think the reason I kept getting so emotional was that growing up watching TV, I never saw anyone on TV that I can identify with. Let alone a superhero, you know?
''And I've always had this saying ... well, not me, but Oscar Wilde ... which is be yourself because everyone else is taken. I've lived by that motto and the second motto when I came into the industry was, be the person you needed when you were younger.
''I feel like one motto led me to the other and, you know, I kept crying about it.''
The character of Batwoman first appeared in comic books as a romantic interest for Batman.
But she has been openly gay in the comics since 2006, when she was reintroduced as a lesbian of Jewish descent.
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