The two music mega stars have made the shortlist for the prestigious prize, which is set to be handed out at a glitzy ceremony held at the Grosvenor House Hotel on July 6, with Anne-Marie presenting the trophy to either of her pals.
The 'Perfect' hitmaker and 'Shut Up' grime star find themselves nominated in the fan-voted category amongst some of the best live performers in the world.
Julie Whelan, chief executive of the Nordoff Robbins music charity, said: ''At Nordoff Robbins we know the power of music - how it resonates with us all on a very personal level, so it is always so exciting to see who the public choose as their Best Live Act; the group or person whose music has had a real impact on their lives.
''The nominees highlight some of the best of the music industry and I'm sure their fans will be voting furiously to ensure their favourite act takes home the award.''
Voting is open now for fans to have their say before June 25, and they can show their support both on Ticketmaster or Twitter over the next three weeks.
Nordoff Robbins O2 Silver Clef Awards - Best Live Act nominees:
Fall Out Boy
Jeff Lynne's ELO
From their newest EP 'What Did You Think When You Made Me This Way', Nothing But Thieves drop the lyric video for their single 'Take This Lonely...
The Lumineers honour their friend and hero Tom Petty with a sensational cover of his 1996 song 'Walls' from the 'She's the One' soundtrack.
Watch Olly Murs get his nerd on as he blags his way into an exclusive Snoop Dogg party (where Rowan Atkinson is the bartender) in the video for their...
From 'Happy' to 'Banana Pancakes', these are soaked in positivity.
Mariah Carey is the picture of glamour in the black and white video for her brand new single 'With You'. It's the lead single from her forthcoming...
Eminem draws attention to the negative response his 2017 album 'Revival' received in the video for his latest song 'Venom'; a song recorded for the...
With the recent release of her third, very well received album 'Hunter' just behind her, Anna had plenty of relatively new songs to showcase.
As it's been 12 years since the last Bridget Jones movie, expectations aren't too high...
Bridget has always known how to get herself into a muddle - catastrophic muddles at...
After battling the dating scene and finally finding love with Mark Darcy, Bridget Jones is...
In July of 2015, Ed Sheeran played his biggest gigs to date, selling out Wembley...