The presenter, who has hosted the Channel 4 reality show since it started in 2000, is devastated it is coming to an end next year and is considering seeking a place in the famous house on the final ever series.
She wrote on her Twitter blog: "Well next year we may as well go out with a bang. Think I'll audition ha ha. Yes please (sic)!"
Channel 4 announced the 2010 series of the programme will be the last to air on the station.
Davina admitted she was upset at the decision as she has enjoyed working on the show - which launched the career of the late Jade Goody - so much.
She said: "I have a really amazing feeling watching 'Big Brother 10' now. It's like I want to cherish every second and love it even more, if that's possible.
"I am sad. I just refuse to believe this is the end. It is a sad day for 'Big Brother' fans."
January will see the last series of the celebrity version of the show hit screens, with the normal edition airing in the summer.