Chelsea Handler has blasted Angelina Jolie again.

The chat show host - who is a good friend of Brad Pitt's ex-wife Jennifer Aniston - previously branded Angelina, 41, a lunatic and has now called his divorce from the star an ''emancipation''.

Introducing Angelina's divorce lawyer and her own good friend, Laura Wasser, at a charity event in Los Angeles this week, Chelsea said: ''[Laura]'s very dynamic, she's very principled and she's a very accomplished human being.

''And she's such a humanitarian, she's actually currently negotiating Brad Pitt's emancipation.''

TMZ obtained a video of Chelsea making the comments at the A Place Called Home gala.

After Angelina filed for divorce from Brad, 52, in September, Chelsea said: ''There are reports that part of the problem was Brad was allegedly drinking and smoking too much weed. I wonder why he needed to self-medicate. Maybe because he could have been spending the last 12 years at Lake Como hanging out with George Clooney and Matt Damon, instead of being stuck in a house with 85 kids speaking 15 different languages?

''Oh yeah, because he married a lunatic, that's why!''

Chelsea, 41, also went on to joke that she would celebrate the impending divorce by getting married.

She said: ''Brad and Angelina always said they wouldn't get married until everyone could get married. And I always said I wouldn't get married until they got divorced. So I'm officially accepting proposals! I'm ready!

''But we should all respect their privacy during this very difficult time. So, this will be the last time I speak of this ...on TV. You can follow me on Twitter.''

And in 2010, she called her a ''homewrecker'', saying: ''She's a homewrecker, she is. She can rescue as many babies from as many countries as she wants to, I don't believe you.''