The 'Think Twice' singer will perform 70 shows a year for the next three years, at The Colosseum at Caesars Palace after signing a multi-million dollar deal.
Celine said: "It's happening! Great songs, great lyrics. I think it's going to be very touching."
The Canadian songstress will be backed by 31 musicians for the shows, which include a special section where she performs songs from people's favourite movies.
Celine added the set will feature: "All the songs from my repertoire that people want to hear, And I just love the big orchestra and the beautiful black-and-white movies and romance."
Celine most recently finished a five year run of shows at the same venue in 2007.
The singer's announcement comes a day after Barbra Streisland turned down a £100 million offer to appear in the desert city.
Celine said she is to juggle the performances with caring for her 9-year-old son Rene-Charles by her husband and manager Rene Angelil, and the couple are presently trying to get pregnant for a second baby.
Celine's last run of concerts grossed more than $400 million.
The 'My Heart Will Go On' singer will start the residency in March next year.
Where the 2011 reboot felt effortless in the way it recaptured that warmly anarchic Muppets...
Kermit and friends are set to go international with the help of their unfortunately named...
Kermit and friends return, embarking on an extensive world tour that sees them reach all...