The cartoon series which featured regulars like Brittany Murphy, Kathy Najimy and Tom Petty has been scrapped after 13 series.
King of The Hill will end after the 13 episodes of the 13th series air on U.S. network Fox during the 2009/2010 TV season.
Other celebrities who appeared as voices on the show include Lisa Kudrow, Trace Adkins, Pamela Anderson, Jennifer Aniston, Gary Busey, Johnny Depp and Sally Field.
Green Day and ZZ Top also appeared on the show, which was co-created by Beavis + Butthead animator Mike Judge.