Brad Pitt's oddball character from hit Terry Gilliam film 12 Monkeys has had a sex change for the upcoming Tv spin-off.

Pitt's Jeffrey Goines becomes mental patient Jennifer Goines in the new series, and actress Emily Hampshire has signed on to play her.

Aaron Stanford, Kirk Acevedo and Tom Noonan have also joined the cast of the project, which will officially begin production in Toronto, Canada next week (beg04Aug14).

The show will debut on America's Syfy network in January (15).