The Ghostbusters star led the crowd through the iconic song on Friday (28Oct16) at Chicago's Wrigley Field as he cheered on his beloved Cubs baseball team as they played their first World Series home game since 1945.

Murray's enthusiasm bubbled over as he gave a rousing speech before he began to sing the song, which he bizarrely performed in the style of the Looney Tunes animated character Daffy Duck.

"It's the bottom of the 7th inning, the last chance to order beer. But we didn't come here to drink beer; we came here to win this ballgame," Murray yelled to the Wrigley crowd.

"In order to sing the right lyric - 'Take me out to the crowd' – you need to sing it like our greatest American entertainer, Mr. Daffy Duck. So I want you to spray it and don't say it," he added.

The 66-year-old actor then led the fans in the singing of the baseball anthem in the style of the cartoon duck, accentuating his S's so they spat saliva.

"Let's get some runs, suckers," Murray shouted after the song ended.

Unfortunately, the Cubs went on to lose the game on Friday against the Cleveland Indians 1-0, and then lost again on Saturday (29Oct16) with a score of 7-2.

The Indians now have a 3-1 lead in the best-of-seven series and can clinch the World Series title at Chicago's Wrigley Field on Sunday (30Oct16).