The Mean Girls star has taken a swipe at the singer over her new commercial for her Sweet Like Candy fragrance, which imagines a world full of Grande clones.
Lohan wrote: "Too much makeup" in a tweet linked to early promos, prompting Ariana's fans to lash out at the actress.
One 'Arianator' wrote: "Lindsay, Lindsay, Lindsay... like the girl is happy with her look, too much makeup or not... (Your) comment was unnecessary," while another added: "Ur stupid. Ur supposed to wear a lot of makeup when ur doing a tv show. Duh."
Ariana, who performed with Nicki Minaj at the American Music Awards on Sunday night (20Nov16), has yet to comment.